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Diagnostic Biosystems CYTOKERATIN 5AND14 Cytokeratin 5/14

Supplier:  Diagnostic Biosystems PDM140

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This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as the 50 kDa cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58 kDa protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas ofskin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and existsin combination with cytokeratin 15. This antibody can be useful to distinguish stratified epithelial cellsfrom simple epithelial cells.

Catalog No. 50-238-5542


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