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Invitrogen™ Cytokeratin 7 Monoclonal Antibody (OV-TL12/30)
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Catalog No. 180234
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18-023-4 1 mL
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Catalog No. 18-023-4 Supplier Invitrogen™ Supplier No. 180234
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Description

Mouse Monoclonal Antibody

The 54 kDa protein, cytokeratin 7, is found in most glandular and transitional epithelia. It has detected cytokeratin 7 in a large number of epithelial cell types, including many ductal and glandular epithelia by immunohistochemistry of paraffin-embedded tissue. Primarily, cytokeratin 7 antibody does not react with stratified squamous epithelia but is reactive with transitional epithelium of the urinary tract. Positive tissue: Pancreas/bladder cancer. This antibody is specific for cytokeratin 7, and does not exhibit cross-reactivity with other filament types, including vimentin, desmin, glial fibrillary acidic protein and neurofilament protein. Expected Staining Pattern: Cytoplasmic.

Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
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Specifications

Antigen Cytokeratin 7
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OV-TL12/30
Concentration 0.03755 mg/mL
Conjugate Unconjugated
Dilution Concentrate Antibody
Formulation PBS with 1% BSA and 0.1% sodium azide
Gene KRT7
Gene Accession No. P08729
Gene Alias CK7; CK-7; Cytokeratin 7; cytokeratin-7; D15Wsu77e; K2C7; K7; Kb7; keratin 7; keratin 7, type II; keratin associated protein 7.1; keratin complex 2, basic, gene 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 7; Keratin-7; keratin-associated protein 7-1; keratin-associated protein 7-1-like protein; Krt2-7; KRT7; krt7 {ECO:0000250; LOC100755511; LOC100861181; NACHT, LRR and PYD domains-containing protein 3; sarcolectin; SCL; si:ch73-233m11.1; si:ch73-233m11.2; similar to keratin 7; type II keratin Kb7; type II mesothelial keratin K7; type-II keratin Kb7; UniProtKB:P08729}
Gene Symbols KRT7
Host Species Mouse
Immunogen OTN11 human ovarian carcinoma cells.
Molecular Weight of Antigen 54kDa
Positive Control Pancreas/Bladder cancer
Purification Method Purified
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3855
Packaging 1 Each
Test Specificity This antibody is specific for cytokeratin 7, and does not exhibit cross-reactivity with other filament types, including vimentin, desmin, glial fibrillary acidic protein and neurofilament protein
Includes 0.1% Sodium azide
Target Species Human
Content And Storage 2-8°C
Product Type Antibody
Form Liquid
Isotype IgG1
Host abrv Ms
Reactivity Human
Shipping Condition Wet Ice
Reactivity abrv Hu
Target Gene Cytokeratin 7
Validated Application abrv IHC (FFPE)
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