Invitrogen™ Cytokeratin 8/18 Monoclonal Antibody (Zym5.2 (UCD/PR.10-11))

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 180213

Catalog No. 18-021-3

Description

This monoclonal antibody reacts with human cytokeratins 8 and 18, low molecular weight cytokeratins found in simple epithelium and secretory epithelium. Clone Zym5.2 will react with adenocarcinoma, mesothelioma, and carcinoma derived from simple epithelia, but will not react with stratified squamous epithelia. Positive tissue: Normal colon.Clone/PAD: Zym5.2 (UCD/PR.10-11)Immunogen: Human keratin 8 & 18Specificity: Cytokeratin 8 (52.5 kDa) and 18 (45 kDa) Expected Staining Pattern: Cytoplasmic and membrane.

Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18 (type A; acidic subfamily of low molecular weight keratins).

Specifications

• Antigen: Cytokeratin 8/18
• Classification: Monoclonal
• Concentration: 0.34443 mg/mL
• Dilution: Concentrate Antibody
• Gene: KRT8
• Gene Alias: AA960620; AL022697; AU019895; CARD2; cell proliferation-inducing gene 46 protein; CK18; CK-18; CK8; CK-8; CYK18; CYK8; cytokeratin 18; cytokeratin 8; cytokeratin endo A; Cytokeratin endo B; cytokeratin-18; Cytokeratin-8; Endo B; EndoA; K18; K2C8; K8; keratin 18; keratin 18, type I; keratin 8; keratin 8, type II; keratin complex 1, acidic, gene 18; keratin complex 2, basic, gene 8; keratin D; Keratin, type I cytoskeletal 18; keratin, type II cytoskeletal 8; Keratin-18; keratin-8; Kerd; KO; Krt1-18; KRT18; Krt-2.8; Krt2-8; Krt8; PIG46; Type-II keratin Kb8
• Host Species: Mouse
• Positive Control: Normal colon
• Quantity: 1 mL
• Primary or Secondary: Primary
• Packaging: 1 Each
• Includes: 0.1% Sodium azide
• Content And Storage: 2-8°C
• Form: Liquid
• Reactivity: Human
• Reactivity abrv: Hu
• Validated Application abrv: IHC (FFPE)

• Applications: Immunohistochemistry (Paraffin), Immunohistochemistry (FFPE)
• Clone: Zym5.2 (UCD/PR.10-11)
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA and 0.1% sodium azide
• Gene Accession No.: P05783, P05787
• Gene Symbols: KRT18, KRT8
• Immunogen: Human keratin 8 & 18.
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 3856, 3875
• Test Specificity: Cytokeratin 8 (52.5kDa) and 18 (45kDa)
• Target Species: Human
• Product Type: Antibody
• Host abrv: Ms
• Shipping Condition: Wet Ice
• Target Gene: Cytokeratin 8/18