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Invitrogen™ Cytokeratin 8 Monoclonal Antibody (C-51)
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Catalog No. 01675008
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100 μg
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Catalog No. Quantity
01-675-008 100 μg
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Catalog No. 01-675-008 Supplier Invitrogen™ Supplier No. MA119035
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Description

Mouse Monoclonal Antibody

This antibody recognizes cytokeratin 8 (52.5 kDa). Cytokeratins are members of intermediate filaments subfamily of intracellular proteins represented in epithelial tissues. This antibody will not cross-react with mouse, Xenopus, rat, canine, chicken or rabbit.

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
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Specifications

Antigen Cytokeratin 8
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone C-51
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene KRT8
Gene Accession No. P05786, P05787
Gene Alias AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8
Gene Symbols KRT8
Host Species Mouse
Immunogen Cytoskeleton preparation from HeLa cells.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100152077, 101110495, 281269, 3856
Target Species Human, Bovine, Sheep, Pig
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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