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Invitrogen™ Cytokeratin 8 Polyclonal Antibody
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Catalog No. PIPA529607
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100 μL
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PIPA529607 100 μL
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Catalog No. PIPA529607 Supplier Invitrogen™ Supplier No. PA529607
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, HeLa, mouse liver, rat liver. Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (83%), Xenopus laevis (85%), Dog (91%), Pig (91%), Rhesus Monkey (99%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cytokeratin 8
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.12 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol, 1% BSA and 0.025% ProClin 300, pH 7
Gene KRT8
Gene Accession No. P05787, P11679, Q10758
Gene Alias AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8
Gene Symbols KRT8
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Cytokeratin 8. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16691, 25626, 3856
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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