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Invitrogen™ DAND5 Polyclonal Antibody
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Catalog No. PIPA583970
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PIPA583970 100 μL
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Catalog No. PIPA583970 Supplier Invitrogen™ Supplier No. PA583970
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GMCKAVPFVQ VFSRPGCSAI RLRNHLCFGH CSSLYIPGSD PTPLVLCNSC MPARKRWAPV VLWCLTGSSA SRRRVKISTM LIEGCHCSPK A Highest antigen sequence indentity to the following orthologs: Rat - 65%, Mouse - 65%.

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAND5
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DAND5
Gene Accession No. Q8N907
Gene Alias CER2; CER2CRL2; cerberus 2; Cerberus like-2; cerberus-like 2; cerberus-like protein 2; Cerl2; Cerl-2; Cerr2; CKTSF1B3; CKTSF1B3MGC126849; coco; CRL2; Cysteine knot superfamily 1, BMP antagonist 3; DAN domain BMP antagonist family member 5; DAN domain family member 5; DAN domain family member 5, BMP antagonist; DAN domain family, member 5; Dand5; DANTE; Dte; FLJ38607; GREM3; GREM3cerberus 2; gremlin-3; MGC126849; SP1
Gene Symbols DAND5
Host Species Rabbit
Immunogen Recombinant protein fragment of Human DAND5 (Product #RP-99178)
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 199699
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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