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Invitrogen™ DAP5 Polyclonal Antibody
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Catalog No. PIPA5120841
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PIPA5120841 100 μL
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Catalog No. PIPA5120841 Supplier Invitrogen™ Supplier No. PA5120841
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, 293T, Jurkat, LO2, Mouse brain. Immunogen sequence: PKTINQIRQD AVKDLGVFIP APMAQGMRSD FFLEGPFMPP RMKMDRDPLG GLADMFGQMP GSGIGTGPGV IQDRFSPTMG RHRSNQLFNG HGGHIMPPTQ SQFGEMGGKF MKSQGLSQLY HNQSQGLLSQ LQGQSKDMPP RFSKKGQLNA DEISLRPAQS FLMNKNQVPK L.

CDK5RAP2 is a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein is localized to the centrosome and Golgi complex and interacts with CDK5R1 and pericentrin (PCNT). CDK5RAP2 plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAP5
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene Eif4g2
Gene Accession No. P78344, Q62448
Gene Alias AA589388; AAG1; aging-associated protein 1; DAP5; DAP-5; Death-associated protein 5; E130105L11Rik; eIF4G 2; eIF-4G 2; EIF4G2; eif4g2.L; eif4g2.S; eIF-4-gamma 2; Eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4 gamma, 2; eukaryotic translation initiation factor 4 gamma, 2 L homeolog; eukaryotic translation initiation factor 4 gamma, 2 S homeolog; eukaryotic translation initiation factor 4 gamma, 2 S homeolog; eukaryotic translation initiation factor 4, gamma 2; eukaryotic translation initiation factor 4G-like 1; FLJ41344; NAT1; Natm1; Novel APOBEC-1 target 1; OK/SW-cl.75; p97; translation repressor NAT1; XELAEV_18024574mg
Gene Symbols Eif4g2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 320-490 of human EIF4G2/p97 (NP_001409.3).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13690, 1982, 361628
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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