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Invitrogen™ DAPK1 Polyclonal Antibody
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Catalog No. PIPA517055
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100 μL
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PIPA517055 100 μL
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Catalog No. PIPA517055 Supplier Invitrogen™ Supplier No. PA517055
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAPK1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene DAPK1
Gene Accession No. P53355, Q80YE7
Gene Alias D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Gene Symbols DAPK1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding Gly903 of human DAPK1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1612, 306722, 69635
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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