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Abcam DAPT, Gamma-Secretase Inhibitor, >99% Purity, Solid, 10 mg

Catalog No. 502584578
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50-258-4578 10 mg
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Catalog No. 50-258-4578 Supplier Abcam Supplier No. AB12063310MG
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Potent blood-brain barrier permeable gamma-secretase inhibitor for Notch signaling studies with over 99% purity.

  • Molecular Weight: 432.5 Da
  • Purity: >99%
  • Form: Solid
  • Mechanism of Action: γ-Secretase inhibitor that inhibits Notch signalling in vitro
  • Biological Activity: Inhibits total Aβ and Aβ42 production in human primary cultures (IC50 values are 115 and 200 nM, respectively) with no effect on APPα and APPβ levels
  • Key Properties: Blood-brain barrier permeable; 3D growth matrix component and component of cerebral organoid differentiation media
  • Storage: Store at +4°C

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Target Molecule γ-Secretase
Shipping Condition Ambient
Buffer 100% DAPT
Content And Storage Store at 4°C.
Form Solid
Formulation 100% DAPT
Quantity 10 mg
For Use With (Application) Inhibition of Notch signalling, 3D growth matrix component, cerebral organoid differentiation
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