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Abcam DAPT, Gamma-Secretase Inhibitor, >99% Purity, Solid, 10 mg
Description
- Molecular Weight: 432.5 Da
- Purity: >99%
- Form: Solid
- Mechanism of Action: γ-Secretase inhibitor that inhibits Notch signalling in vitro
- Biological Activity: Inhibits total Aβ and Aβ42 production in human primary cultures (IC50 values are 115 and 200 nM, respectively) with no effect on APPα and APPβ levels
- Key Properties: Blood-brain barrier permeable; 3D growth matrix component and component of cerebral organoid differentiation media
- Storage: Store at +4°C
The product is subject to the following: Abcam Restricted Use Statement
Specifications
Specifications
| Target Molecule | γ-Secretase |
| Shipping Condition | Ambient |
| Buffer | 100% DAPT |
| Content And Storage | Store at 4°C. |
| Form | Solid |
| Formulation | 100% DAPT |
| Quantity | 10 mg |
| For Use With (Application) | Inhibition of Notch signalling, 3D growth matrix component, cerebral organoid differentiation |
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