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Tocris Bioscience™ Davunetide
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Catalog No. 67791
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67-791 1 mg
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Catalog No. 67-791 Supplier Tocris Bioscience™ Supplier No. 6779/1
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Description

Highly potent active component of ADNP; prevents amyloid β aggregation; active in vivo

Davunetide is a highly potent active component of activity-dependent neuroprotective protein (ADNP). Prevents β-amyloid aggregation. Reduces hyperphosphorylated tau levels and increases tau-microtubule interactions; neuroprotective at femtomolar concentrations in vitro. Exerts neuroprotective effects in schizophrenia models associated with microtubule-autophagy insufficiency in MAP6-deficient mice. Modulates HIFs and VEGF expression and suppresses retinal cell apoptosis in an in vivo diabetic retinopathy model.

Specifications

Purity 95%
Content And Storage Store at -20°C
Gene Alias AL-108, NAP (peptide), NAPVSIPQ
Molecular Weight (g/mol) Observed: 824.93
Quantity 1 mg
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