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DAXX Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501560159
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Quantity:
100 μL
Catalog No. Quantity
50-156-0159 100 μL
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Catalog No. 50-156-0159

Supplier: Bethyl Laboratories, Inc A301353A

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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Specifications

Antigen DAXX
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene DAXX
Gene Accession No. Q9UER7
Gene Alias Death domain-associated protein 6, Fas death domain-associated protein, ETS1-associated protein 1, EAP1
Gene Symbols DAXX
Host Species Rabbit
Immunogen Between 466 and 516
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1616
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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