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Ddit3 Monoclonal Antibody (9C8), Active Motif™
SDP

Catalog No. 501993334
Encompass
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50-199-3334 10 μg
50-199-3333 100 μg
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Catalog No. 50-199-3334 Supplier Active Motif Supplier No. 61350
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Description

Mouse Monoclonal Antibody

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.

Specifications

Antigen Ddit3
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 9C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene DDIT3
Gene Accession No. P35639
Gene Alias C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; DDIT3; DDIT-3; DNA damage inducible transcript 3; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; Gadd153; Growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154
Gene Symbols DDIT3
Host Species Mouse
Immunogen This antibody was raised against full-length recombinant mouse Ddit3 protein.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13198
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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