Ddit3 Monoclonal Antibody (9C8), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 61350

Catalog No. 50-199-3334

Description

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.

Specifications

• Antigen: Ddit3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Accession No.: P35639
• Gene Symbols: DDIT3
• Immunogen: This antibody was raised against full-length recombinant mouse Ddit3 protein.
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunoprecipitation, Western Blot
• Clone: 9C8
• Conjugate: Unconjugated
• Gene: DDIT3
• Gene Alias: C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; DDIT3; DDIT-3; DNA damage inducible transcript 3; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; Gadd153; Growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 13198
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid