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Ddit3 Monoclonal Antibody (9C8), Active Motif™

Mouse Monoclonal Antibody
$132.55 - $397.65
Specifications
Antigen | Ddit3 |
---|---|
Clone | 9C8 |
Concentration | 1 mg/mL |
Applications | Immunoprecipitation, Western Blot |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3334
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Active Motif
61350 |
10 μg |
Each for $132.55
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50-199-3333
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Active Motif
61349 |
100 μg |
Each for $397.65
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Description
GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.Specifications
Ddit3 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5 | |
C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; DDIT3; DDIT-3; DNA damage inducible transcript 3; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; Gadd153; Growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154 | |
DDIT3 | |
IgG2b | |
Protein G | |
Antibody |
9C8 | |
Immunoprecipitation, Western Blot | |
Unconjugated | |
Mouse | |
Mouse | |
P35639 | |
13198 | |
This antibody was raised against full-length recombinant mouse Ddit3 protein. | |
Primary | |
-20°C, Avoid Freeze/Thaw Cycles | |
DDIT3 |
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