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Ddit3 Mouse anti-Mouse, Clone: 9C8, Active Motif™ 
Mouse Monoclonal Antibody
$116.85 - $356.95
Specifications
| Monoclonal or Polyclonal | Monoclonal |
|---|---|
| Primary or Secondary | Primary |
| Antigen | Ddit3 |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
50-199-3334
|
Active Motif
61350 |
10 μg |
Each for $116.85
|
|
50-199-3333
|
Active Motif
61349 |
100 μg |
Each for $356.95
|
|
Description
GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.Specifications
| Monoclonal | |
| Primary | |
| Ddit3 | |
| Unconjugated |
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