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Apexbio Technology LLC DDR1-IN-1 1449685-96-4 10mg
Supplier: Apexbio Technology LLC B338310
DDR1-IN-1 (CAS 1449685-96-4) is a small-molecule inhibitor that selectively targets discoidin domain receptor 1 (DDR1) a receptor tyrosine kinase implicated in cell adhesion migration and extracellular matrix remodeling DDR1-IN-1 exhibits high potency against DDR1 with reported IC50 and EC50 values of 105 nM and 87 nM respectively The compound demonstrates reduced activity toward DDR2 showing a 4-fold higher IC50 (413 nM) DDR1-IN-1 is utilized in biomedical research to investigate DDR1-mediated signaling pathways and to explore the therapeutic potential of DDR1 inhibition in disease models involving aberrant receptor activation
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