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Invitrogen™ Decorin Polyclonal Antibody
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Catalog No. PIPA513538
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400 μL
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PIPA513538 400 μL
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Catalog No. PIPA513538 Supplier Invitrogen™ Supplier No. PA513538
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine and porcine based on sequence homology.

Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Decorin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene DCN
Gene Accession No. P07585, P28654
Gene Alias Bone proteoglycan II; CSCD; DC; Dcn; DCN protein; DCN1C; Decorin; decorin isoform a preproprotein; Dermatan sulfate proteoglycan-II; dermatan sulfate proteoglycan-II (decorin); dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); DSPG; DSPG2; mDcn; PG40; PGII; PGS2; PG-S2; proteoglycan core protein; proteoglycan core protein; binds type I collagen fibers and TGF-beta; decoron; similar to bone proteoglycan II; similar to decorin; SLRR1B; Small leucine rich protein 1B; small leucine-rich protein 1B; unnamed protein product
Gene Symbols DCN
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 122-150 amino acids from the central region of human DCN.
Purification Method Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13179, 1634
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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