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Invitrogen™ DEFA1 Monoclonal Antibody (2D2)
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Catalog No. PIMA534894
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100 μL
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PIMA534894 100 μL
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Catalog No. PIMA534894 Supplier Invitrogen™ Supplier No. MA534894
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Description

Mouse Monoclonal Antibody

Positive Control: Rat spleen tissue, human spleen tissue.

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DEFA1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2D2
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene DEFA1
Gene Accession No. P59665
Gene Alias alpha-defensin 1; Cryptdin-1; DEF1; Defa1; DEFA1B; DEFA2; Defcr; Defcr1; defensin alpha 1; defensin related cryptdin peptide 1; defensin, alpha 1; defensin, alpha 1, myeloid-related sequence; defensin, alpha 2; defensin-1; defensin-related cryptdin peptide; HNP-1; HNP-2; HP 1-56; HP1; HP-1; HP-2; MRS; myeloid-related sequence; neutrophil defensin 1; Neutrophil defensin 2
Gene Symbols DEFA1
Host Species Mouse
Immunogen Synthetic peptide within Human HNP-1 aa 1-50.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1667
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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