DEFB121 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 257611AP150UL

Catalog No. 50-173-5060

Description

Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, beta-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other beta-defensins, it does not appear to be regulated by androgens.

Specifications

• Antigen: DEFB121
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DEFB121
• Gene Alias: Beta defensin 121, Beta defensin 21, DEFB 21, DEFB121, DEFB21, defensin, beta 121, ESC42 RELC
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 245934
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q5J5C9
• Gene Symbols: DEFB121
• Immunogen: DEFB121 Fusion Protein Ag22712
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG