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DEFB121 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735060 Shop All Proteintech Group Inc Products
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50-173-5060 150 μL
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Catalog No. 50-173-5060 Supplier Proteintech Group Inc Supplier No. 257611AP150UL
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Description

Rabbit Polyclonal Antibody

Beta-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, beta-defensins are developmentally regulated. The family of beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many beta-defensins also are involved in sperm maturation and capacitation. beta-defensin 121 is a 76 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. While expressed at low levels in testis, beta-defensin 121 is abundantly expressed in epididymal caput and corpus and, unlike other beta-defensins, it does not appear to be regulated by androgens.

Specifications

Antigen DEFB121
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DEFB121
Gene Accession No. Q5J5C9
Gene Alias Beta defensin 121, Beta defensin 21, DEFB 21, DEFB121, DEFB21, defensin, beta 121, ESC42 RELC
Gene Symbols DEFB121
Host Species Rabbit
Immunogen DEFB121 Fusion Protein Ag22712
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 245934
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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