Invitrogen™ degP Polyclonal Antibody

Catalog No.	Quantity
FEPA5144492	100 μL

Catalog No. FEPA5144492 Supplier Invitrogen™ Supplier No. PA5144492

Description

Rabbit Polyclonal Antibody

degP Polyclonal Antibody for Western Blot, ELISA

DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures (PubMed:10319814). Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm following heat shock or other stress conditions (PubMed:16303867). DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids (PubMed:8830688). Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-specific proteolysis of folded proteins (PubMed:8830688). Its proteolytic activity is essential for the survival of cells at elevated temperatures (PubMed:7557477). It can degrade IciA, Ada, casein, globin and PapA. DegP shares specificity with DegQ (PubMed:8830688). DegP is also involved in the biogenesis of partially folded outer-membrane proteins (OMP).

Specifications

• Antigen: degP
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene: degP
• Gene Accession No.: P0C0V0
• Gene Alias: htrA; ptd
• Gene Symbols: degP
• Host Species: Rabbit
• Immunogen: Recombinant Escherichia coli Periplasmic serine endoprotease DegP (degP) (27-474AA).
• Purification Method: Protein A/G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 75202024
• Target Species: Bacteria
• Content And Storage: -20°C or -80°C if preferred
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG