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Invitrogen™ Dehydroepiandrosterone Polyclonal Antibody
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Catalog No. PIPA175101
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Quantity:
1 mg
Catalog No. Quantity
PIPA175101 1 mg
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Catalog No. PIPA175101

Supplier: Invitrogen™ PA175101

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Sheep Polyclonal Antibody

Working Concentration: 0.625 μg/mL. Sensitivity: 10 ng/mL DHEA produces 74% inhibition in a competitive ELISA employing Dehydroepiandrosterone (DHEA-17) polyclonal antibody.

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. DHEA is also produced in the gonads, adipose tissue and the brain. DHEA is structurally similar to, and is a precursor of, androstenedione, testosterone, estradiol, estrone and estrogen. It is the most abundant hormone in the human body. Most of DHEA is sulfated (dehydroepiandrosterone sulfate- DEHAS) before secretion. DHEAS is the sulfated version of DHEA; - this conversion is reversibly catalyzed by sulfotransferase (SULT2A1) primarily in the adrenals, the liver, and small intestines. In blood, most DHEA is found as DHEAS with levels that are about 300 times higher than free DHEA. Blood measurements of DHEAS/DHEA are useful to detect excess adrenal activity as seen in adrenal cancer or hyperplasia, including certain forms of congenital adrenal hyperplasia. Women with polycystic ovary syndrome tend to have normal or mildly elevated levels of DHEAS. [National Center for Biotechnology Information. PubChem Compound Database; CID=5881].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dehydroepiandrosterone
Applications ELISA
Classification Polyclonal
Concentration 13.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Alias Androstenolone; C19H28O2; dehydroepiandrosterone sulfate; Dehydroisoandrosterone; DHEA; PRASTERONE
Host Species Sheep
Immunogen DHEA(17)-BTG.
Purification Method Purified
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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