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Dendritic Cell Marker DCIR2 Rat anti-Mouse, PE, Clone: 33D1, eBioscience™
Rat Monoclonal Antibody
$228.00 - $298.00
Specifications
| Antigen | Dendritic Cell Marker DCIR2 |
|---|---|
| Clone | 33D1 |
| Target Species | Mouse |
| Conjugate | PE |
| Isotype | IgG2b κ |
Description
Description: The 33D1 monoclonal antibody reacts with a mouse dendritic cell (DC)-specific surface marker, DCIR2. The nature and biological activity of DCIR2 is unknown. DCIR2 has been reported on a variety of dendritic cell subpopulations from mouse thymus, spleen, lymph node, and Peyer′s patch. Bone marrow dendritic cells require GM-CSF to express DCIR2, and this expression is downregulated in the presence of IL-4. DCIR2 has been detected in vivo in brain dendritic cells post infection with Toxoplasma gondii. Applications Reported: The 33D1 antibody has been reported for use in flow cytometric analysis. Applications Tested: The 33D1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.
The nature and biological activity of DCIR2 is unknown. DCIR2 has been reported on a variety of dendritic cell subpopulations from mouse thymus, spleen, lymph node, and Peyer′s patch. Bone marrow dendritic cells require GM-CSF to express DCIR2, and this expression is downregulated in the presence of IL-4. DCIR2 has been detected in vivo in brain dendritic cells post infection with Toxoplasma gondii.Specifications
| Dendritic Cell Marker DCIR2 | |
| Mouse | |
| IgG2b κ | |
| Primary | |
| Monoclonal | |
| PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2 | |
| RUO |
| 33D1 | |
| PE | |
| Flow Cytometry | |
| Liquid | |
| Antibody | |
| 4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.
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