Invitrogen™ DENND1A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570324

Catalog No. PIPA570324

Description

This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 93%.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Specifications

• Antigen: DENND1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DENND1A
• Gene Alias: 6030446I19Rik; connecdenn; Connecdenn 1; DENN domain containing 1A; DENN domain-containing protein 1A; DENN domain-containing protein 1A pseudogene; DENN/MADD domain containing 1A; DENND1A; FAM31A; KIAA1608; LOW QUALITY PROTEIN: DENN domain-containing protein 1A; Protein FAM31A; RGD1307927; RP11-230L22.3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 227801
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Surface Plasmon Resonance
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8K382
• Gene Symbols: DENND1A
• Immunogen: synthetic peptide directed towards the middle region of human DENND1A (aa 585-634).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG