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Invitrogen™ DENND1A Polyclonal Antibody
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Catalog No. PIPA570324
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PIPA570324 100 μL
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Catalog No. PIPA570324 Supplier Invitrogen™ Supplier No. PA570324
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Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 93%.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2). Thus, connecdenns link RAB35 activation with the clathrin machinery.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DENND1A
Applications Western Blot, Surface Plasmon Resonance
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene DENND1A
Gene Accession No. Q8K382
Gene Alias 6030446I19Rik; connecdenn; Connecdenn 1; DENN domain containing 1A; DENN domain-containing protein 1A; DENN domain-containing protein 1A pseudogene; DENN/MADD domain containing 1A; DENND1A; FAM31A; KIAA1608; LOW QUALITY PROTEIN: DENN domain-containing protein 1A; Protein FAM31A; RGD1307927; RP11-230L22.3
Gene Symbols DENND1A
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human DENND1A (aa 585-634).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227801
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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