DENND1A Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5009	150 μL

Catalog No. 50-173-5009 Supplier Proteintech Group Inc Supplier No. 256581AP150UL

Description

Rabbit Polyclonal Antibody

This antibody (25658-1-AP) can recognize all isoforms at 112 kDa and 52-64 kDa.

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2). Thus, connecdenns link RAB35 activation with the clathrin machinery.

Specifications

• Antigen: DENND1A
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.31 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: DENND1A
• Gene Accession No.: Q8TEH3
• Gene Alias: Connecdenn, DENN/MADD domain containing 1A, DENND1A, FAM31A, KIAA1608, Protein FAM31A, RP11 230L22.3
• Gene Symbols: DENND1A
• Host Species: Rabbit
• Immunogen: DENND1A Fusion Protein Ag22547
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57706
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG