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Invitrogen™ DERL2 Polyclonal Antibody
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Catalog No. PIPA561845
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100 μL
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PIPA561845 100 μL
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Catalog No. PIPA561845 Supplier Invitrogen™ Supplier No. PA561845
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NYNPLPEERP GGFAWGEGQR LGG Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DERL2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DERL2
Gene Accession No. Q9GZP9
Gene Alias carcinoma related; CGI-101; Degradation in endoplasmic reticulum protein 2; Der1-like domain family, member 2; der1-like protein 2; Der2; Derl2; derlin 2; derlin-2; derlin-2-like; DERtrin-2; F-LAN-1; Flana; F-LANa; LOC100910823; SBBI53
Gene Symbols DERL2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DERL2. Recombinant protein control fragment (Product #RP-101113).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51009
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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