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  5. 22161R

Tocris Bioscience™ des-His1-[Glu9)-Glucagon (1-29) amide
GREENER_CHOICE

Catalog No. 22161R
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Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Glucagon receptor antagonist

des-His1-[Glu9]-Glucagon (1-29) amide is a glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitro. Blocks added glucagon-induced hyperglycemia in normal rabbits without affecting glycogenolysis in vivo. Also blocks endogenous glucagon-induced hyperglycemia in streptozocin diabetic rats.

Specifications

Purity 95%
Content And Storage Store at -20°C
Description des-His1-[Glu9)-Glucagon (1-29) amide
Molecular Weight (g/mol) 3358.68
Product Type des-His1-[Glu9]-Glucagon (1-29) amide
Quantity 1 mg
Sequence Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2

For Research Use Only

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