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Cayman Chemical DescarbamylnovobIocIn 5mg

Supplier: Cayman Chemical 299715 MG

A selective adenosine A1 receptor agonist (Kis 3 1 and 1300 nM for adenosine A1 and A2 receptors respectively in rat brain inhibits isoprenaline-induced cAMP accumulation in DDT1MF-2 hamster smooth muscle cells (IC50 2 6 nM) but only decreases contractility in isolated guinea pig atria with an EC50 value of 1500 nM inhibits norepinephrine-induced lipolysis in rat adipocytes (EC50 0 83 nM) decreases locomotor activity and inhibits DMCM-induced seizures in mice (ED50s 0 13 and 0 3 mg/kg respectively) decreases blood pressure by 74 in anesthetized rats at 0 1 mg/kg
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