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Invitrogen™ Desmocollin 2/3 Monoclonal Antibody (7G6)
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Catalog No. 326200
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100 μg
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Catalog No. Quantity
32-620-0 100 μg
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Catalog No. 32-620-0 Supplier Invitrogen™ Supplier No. 326200
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Description

Mouse Monoclonal Antibody

Desmocollin 2/3 Monoclonal Antibody for IHC (P), IP, Western Blot

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmocollin 2/3
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 7G6
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene DSC3
Gene Accession No. Q02487, Q14574
Gene Alias ARVC10; ARVD10; ARVD11; cadherin family member 2; Cadherin family member 3; CDHF2; CDHF3; CDHF5; CDHF6; CMD1BB; desmocollin 2; desmocollin 3; desmocollin-2; Desmocollin-3; desmocollin-4; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; DG2; DGII/III; DSC; DSC1; DSC2; DSC3; DSC4; HDGC; HT-CP; PVA
Gene Symbols DSC2, DSC3
Host Species Mouse
Immunogen Human desmocollin-2 extracellular domain.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1824, 1825
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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