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Invitrogen™ Desmoglein 2 (DSG2) Polyclonal Antibody
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Catalog No. PIPA5121232
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PIPA5121232 100 μL
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Catalog No. PIPA5121232 Supplier Invitrogen™ Supplier No. PA5121232
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HepG2, HeLa, SW620, DU145, K-562. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome. Immunogen sequence: CHCGKGAKGF TPIPGTIEML HPWNNEGAPP EDKVVPSFLP VDQGGSLVGR NGVGGMAKEA TMKGSSSASI VKGQHEMSEM DGRWEEHRSL LSGRATQFTG ATGAIMTTET TKTARATGAS RDMAGAQAAA VALNEEFLRN YFTDKAASYT EEDENHTAKD CLLVYSQEET ESLNASIGCC SFIEGELDDR FLDDLGLKFK TLAEVCLGQK IDINKEIEQR QKPATETSMN TASHSLCEQT MVNSENTYSS GSSFPVPKSL QEANAEKVTQ EIVTERSVSS RQAQKVATPL PDPMASRNVI A.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmoglein 2 (DSG2)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4.96 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene DSG2
Gene Accession No. O55111, Q14126
Gene Alias AA408168; ARVC10; ARVD10; Cadherin family member 5; CDHF5; CMD1BB; D18Ertd293e; desmoglein 2; desmoglein-2; DSG2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037
Gene Symbols DSG2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13511, 1829, 307562
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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