Invitrogen™ Desmoglein 2 Monoclonal Antibody (10D2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA536301

Catalog No. PIMA536301

Description

Tag sequence is: LLPKHPHLVR QKRAWITAPV ALREGEDLSK KNPIAKIHSD LAEERGLKIT YKYTGKGITE PPFGIFVFN KDTGELNVTS ILDREETPFF LLTGYALDAR GNNVEKPLEL RIKVLDIND NEPVFTQDVF Immunogen sequence: LLPKHPHLVR QKRAWITAPV ALREGEDLSK KNPIAKIHSD LAEERGLKIT YKYTGKGITE PPFGIFVFNK DTGELNVTSI LDREETPFFL LTGYALDARGN NVEKPLELRI KVLDINDNEP VFTQDVF.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Specifications

• Antigen: Desmoglein 2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q14126
• Gene Symbols: DSG2
• Immunogen: N terminal amino acids 37-164 of Human Desmoglein 2 fused to a proprietary tag.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 10D2
• Conjugate: Unconjugated
• Gene: DSG2
• Gene Alias: AA408168; ARVC10; ARVD10; Cadherin family member 5; CDHF5; CMD1BB; D18Ertd293e; desmoglein 2; desmoglein-2; DSG2; DSG-2; HDGC; MGC117034; MGC117036; MGC117037
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1829
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov