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Invitrogen™ Desmoplakin Monoclonal Antibody (DP-2.15)
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Catalog No. PIMA183118
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50 μg
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PIMA183118 50 μg
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Catalog No. PIMA183118 Supplier Invitrogen™ Supplier No. MA183118
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Description

Mouse Monoclonal Antibody

Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 recognizes both desmoplakin 1 and 2 from stratified epithelia, simple epithelia including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges. Mouse anti Desmoplakin 1/2 antibody, clone DP-2.15 can be used for the detection of primary and metastatic carcinomas.

Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Desmoplakin
Applications Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone DP-2.15
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with <0.1% sodium azide; pH 7.4
Gene DSP
Gene Accession No. E9Q557, P15924
Gene Alias 2300002E22Rik; 250/210 kDa paraneoplastic pemphigus antigen; 5730453H04Rik; AA407887; AA407888; AW109828; DCWHKTA; dermatan sulfate proteoglycan 3; desmoplakin; desmoplakin I/II; Desmoplakin II; desmoplakin; LOW QUALITY PROTEIN: desmoplakin; Desmoplakin-I; desmosomal cytoskeletal connector molecule; DP; Dsp; dspg3; Oculoglycan; Opt; Optc; optcl; Opticin; rul; SLRP; SLRP protein; small leucine-rich repeat protein; small leucine-rich repeat protein (SLRP); wu:fb81a05; zgc:101047
Gene Symbols DSP
Host Species Mouse
Immunogen Native bovine desmoplakin 1 and 2.
Purification Method Protein A
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109620, 1832, 306871, 420869, 514360
Target Species Human, Mouse, Rat, Bovine, Chicken
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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