Dextran, MW ca 500,000

Description

Dextran, CAS # 9004-54-0, is a glucose polymer. It is mainly used to increase electronegativity and reduce erythrocyte aggregation and platelet adhesiveness (anticoagulant activity). | CAS: 9004-54-0 | (C6H9O5)n(C6H10O5)m | 504.44 g/mol

It is used in increasing the electronegativity and reducing erythrocyte aggregation and platelet adhesiveness and also serves as a plasminogen activator.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Dextran is a glucose polymer biosynthesized by the non-pathogenic Leuconostoc mesenteroides

Application

• Dextran is a complex branched glucan that can be used to enhance electronegativity and reduce erythrocyte aggregation and platelet adhesiveness (anticoagulant activity)
• This compound promotes the activation of plasminogen by inhibiting α-2 antiplasmin
• Dextran can be used to reduce thrombosis in animal models
• It is used in osmotic stress techniques where osmotic pressure is applied to biological molecules
• Dextran can be used as an immobilization agent in biosensors

Specifications

Chemical Identifiers

• CAS: 9004-54-0
• Molecular Formula: (C6H9O5)n(C6H10O5)m
• Molecular Weight (g/mol): 504.44
• MDL Number: MFCD00130935
• InChI Key: FZWBNHMXJMCXLU-UHFFFAOYNA-N
• Synonym: dextran, dextran, mw-86.000 aver., 2,3,4,5-tetrahydroxy-6-3,4,5-trihydroxy-6-3,4,5-trihydroxy-6-hydroxymethyl tetrahydro-2h-pyran-2-yl oxy methyl tetrahydro-2h-pyran-2-yl oxy hexanal, 2,3,4,5-tetrahydroxy-6-3,4,5-trihydroxy-6-3,4,5-trihydroxy-6-hydroxymethyl oxan-2-yl oxymethyl oxan-2-yl oxyhexanal, 2,3,4,5-tetrahydroxy-6-3,4,5-trihydroxy-6-3,4,5-trihydroxy-6-hydroxymethyl tetrahydropyran-2-yl oxymethyl tetrahydropyran-2-yl oxy-hexanal
• PubChem CID: 4125253
• IUPAC Name: Dextran
• SMILES: O[C@@H]1[C@@H](O)[C@@H](-*)O[C@H](CO[C@H]2O[C@H](CO-*)[C@@H](O)[C@H](O-*)[C@H]2O)[C@H]1O

• Color: White
• Physical Form: Powder
• Merck Index: 14,2948
• Solubility Information: Soluble in water,dimethyl sulfoxide,ethylene glycol and glycerol.
• Quantity: 50 g
• Formula Weight: ≈500 kd
• Chemical Name or Material: Dextran

Safety and Handling

EINECSNumber	232-677-5
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only