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Invitrogen™ DGAT2 Polyclonal Antibody
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Catalog No. PIPA518667
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100 μg
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Catalog No. Quantity
PIPA518667 100 μg
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Catalog No. PIPA518667 Supplier Invitrogen™ Supplier No. PA518667
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DGAT2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene DGAT2
Gene Accession No. Q96PD7
Gene Alias 0610010B06Rik; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; DGAT2; DGAT-2; diacylglycerol acyltransferase 2; diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase homolog 2; diacylglycerol O-acyltransferase-like protein 2; diglyceride acyltransferase 2; DKFZp686A15125; GS1999FULL; HMFN1045; LOW QUALITY PROTEIN: diacylglycerol O-acyltransferase 2; putative diacylglycerol O-acyltransferase; retinol O-fatty-acyltransferase; UNQ738/PRO1433
Gene Symbols DGAT2
Host Species Goat
Immunogen Synthetic peptide sequence (KLEHPTQQDIDLYH) corresponding to the internal amino acids of DGAT2 (aa 346-360).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84649
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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