Invitrogen™ DGAT2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518667

Catalog No. PIPA518667

Description

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

Specifications

• Antigen: DGAT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DGAT2
• Gene Alias: 0610010B06Rik; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; DGAT2; DGAT-2; diacylglycerol acyltransferase 2; diacylglycerol O-acyltransferase 2; diacylglycerol O-acyltransferase homolog 2; diacylglycerol O-acyltransferase-like protein 2; diglyceride acyltransferase 2; DKFZp686A15125; GS1999FULL; HMFN1045; LOW QUALITY PROTEIN: diacylglycerol O-acyltransferase 2; putative diacylglycerol O-acyltransferase; retinol O-fatty-acyltransferase; UNQ738/PRO1433
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 84649
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96PD7
• Gene Symbols: DGAT2
• Immunogen: Synthetic peptide sequence (KLEHPTQQDIDLYH) corresponding to the internal amino acids of DGAT2 (aa 346-360).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG