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Apexbio Technology LLC Dihydro-β-erythroidine hydrobromide(Synonyms: DHβE hydrobromide, Dihydro-beta-erythroidine hydrobromide, Dihydro-β-erythroidine HBr), 50mg, CAS: 29734-68-7.
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Supplier:  Apexbio Technology LLC B703050

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Dihydro- -erythroidine hydrobromide (CAS 29734-68-7) abbreviated DH E is a competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs) Acting directly at nAChR subunits DH E blocks acetylcholine-mediated receptor activation in neurons Its inhibitory potency (IC50) varies by receptor subtype notably 0 37 M for 4 2 0 41 M for 3 2 and 0 19 M for 4 4 nAChRs In vivo studies demonstrate DH E s capacity to cross the blood-brain barrier attenuating nicotine-induced central nervous system responses Due to these antagonist properties DH E is frequently utilized as a research tool in studies investigating nAChR function and neuropharmacology

Catalog No. 50-000-61287


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