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Invitrogen™ DHCR24 Polyclonal Antibody
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Catalog No. PIPA576186
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100 μL
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PIPA576186 100 μL
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Catalog No. PIPA576186 Supplier Invitrogen™ Supplier No. PA576186
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of its gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DHCR24
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Dhcr24
Gene Accession No. Q15392, Q5BQE6, Q8VCH6
Gene Alias 2310076D10Rik; 24-dehydrocholesterol reductase; 3 beta-hydroxysterol delta 24-reductase; 3-beta-hydroxysterol delta-24 reductase; 3-beta-hydroxysterol delta-24-reductase; 5830417J06Rik; DCE; Delta(24)-sterol reductase; desmosterol-to-cholesterol enzyme; DHCR24; Diminuto/dwarf1 homolog; KIAA0018; mKIAA0018; Nbla03646; seladin 1; SELADIN1; seladin-1; selective AD indicator 1
Gene Symbols Dhcr24
Host Species Rabbit
Immunogen Recombinant protein of human DHCR24.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1718, 298298, 74754
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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