Diethyl acetamidomalonate, 98+%

Description

CAS: 1068-90-2 | C9H15NO5 | 217.221 g/mol

Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin analogues as potential heat shock protein 90 inhibitors. It is also used as a important intermediates in syntheses of vitamins B1 and B6, barbiturates, non-steroidal anti-inflammatory agents, other numerous pharmaceuticals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin analogues as potential heat shock protein 90 inhibitors. It is also used as a important intermediates in syntheses of vitamins B1 and B6, barbiturates, non-steroidal anti-inflammatory agents, other numerous pharmaceuticals.

Solubility
Soluble in chloroform and methanol. Slightly soluble in water.

Notes
Store in cool, dry place in tightly closed containers. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 1068-90-2
• Molecular Formula: C9H15NO5
• Molecular Weight (g/mol): 217.221
• MDL Number: MFCD00009146
• InChI Key: ISOLMABRZPQKOV-UHFFFAOYSA-N
• Synonym: diethyl acetamidomalonate, diethyl 2-acetamidomalonate, diethyl acetaminomalonate, diethyl acetylaminomalonate, acetamidomalonic acid diethyl ester, 2-acetylaminomalonic acid diethyl ester, 1,3-diethyl 2-acetamidopropanedioate, diethyl acetylamino malonate, propanedioic acid, acetylamino-, diethyl ester, acetylamino propanedioic acid diethyl ester
• PubChem CID: 14041
• IUPAC Name: diethyl 2-acetamidopropanedioate
• SMILES: CCOC(=O)C(C(=O)OCC)NC(=O)C

• Melting Point: 96°C to 99°C
• Boiling Point: 185°C (20 mmHg)
• Quantity: 25 g
• Beilstein: 783883
• Solubility Information: Soluble in chloroform and methanol. Slightly soluble in water.
• Formula Weight: 217.22
• Percent Purity: ≥98%
• Chemical Name or Material: Diethyl acetamidomalonate

Safety and Handling

Hazard Category	H302-H315-H319-H335
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	213-952-9
RTECSNumber	OO0360000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only