Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000091828

Apexbio Technology LLC Anti-CD38 Antibody (Daratumumab) 100ug
SDP

Supplier:  Apexbio Technology LLC F13700.1

Encompass_Preferred

Daratumumab (CAS 945721-28-8) is a monoclonal antibody targeting CD38 a surface glycoprotein highly expressed on plasma cells especially in multiple myeloma (MM) cells It is designed to selectively bind CD38 thereby mediating tumor cell lysis via multiple immune effector mechanisms Daratumumab exerts its biological activity primarily through antibody-dependent cell-mediated cytotoxicity (ADCC) complement-dependent cytotoxicity (CDC) antibody-dependent cellular phagocytosis (ADCP) and direct induction of apoptosis Additionally it inhibits adhesion of MM cells to bone marrow stromal cells potentially increasing sensitivity to proteasome inhibitors Based on these pharmacological properties Daratumumab holds research potential in therapeutic strategies targeting multiple myeloma

Catalog No. 50-000-91828


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.