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Enzo Life Sciences Dimethyloxaloylglycine (50mg). CAS: 89464-63-1

Supplier: Enzo Life Sciences BMLEI3470050

DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic. Alternative name: DMOG, N-(Methoxyoxoacetyl)-glycine methyl ester. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (>25mg/ml), 100% ethanol (>25mg/ml) or dimethyl formamide; soluble also in PBS, pH7.2 (10mg/ml). Long Term Storage: -20°C.
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