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Tocris™ Diminazene aceturate

Catalog No. 6705100
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100 mg
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Catalog No. Quantity
67-051-00 100 mg
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Catalog No. 67-051-00 Supplier Tocris™ Supplier No. 6705/100
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Description

ASIC blocker; antihyperalgesic

Diminazene aceturate is an ASIC blocker (IC50 values are 202, ∽320, ∽320 and 864 nM for ASIC1b, ASIC1a, ASIC3 and ASIC2a, respectively). Exhibits no activity in ENaC channels expressed in oocytes. Accelerates desensitization of ASIC currents in hippocampal neurons. Inhibits mesotrypsin (Ki = 3.6?0.3 μM). Displays in vitro and in vivo anti-inflammatory effects in mice. Antihyperalgesic.

Specifications

Chemical Name or Material 4,4'-(1-Triazene-1,3-diyl)bis[benzenecarboximidamide] bis(N-acetylglycinate)
CAS 908-54-3
Quantity 100 mg
Molecular Formula C14H15N7.2C4H7NO3
Formula Weight 515.52
Product Type ASIC Blocker, Antihyperalgesic
Purity 98%
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