(+)-DIOP, 98%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
It is employed as a ligand for the in situ preparation of chiral hydrogenation catalysts. It also finds it application for the in situ preparation of chiral hydrogenation catalysts, ligand for Rh(I)-catalyzed asymmetric hydrogenation of enamides, 1,4-disilylation of α,β-unsaturated ketones, Heck reaction of alkenyl iodides, and hydroformylation of olefins.

Solubility
Sparingly soluble in water at 25°C 2.1E-5 g/L.

Notes
Air sensitive. Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 37002-48-5
• Molecular Formula: C31H32O2P2
• Molecular Weight (g/mol): 498.543
• MDL Number: MFCD00009760
• InChI Key: VCHDBLPQYJAQSQ-LOYHVIPDSA-N
• Synonym: +-diop, unii-5p52k0ij7t, 4s,5s-2,2-dimethyl-1,3-dioxolane-4,5-diyl bis methylene bis diphenylphosphine, s,s-diop, 4s,5s-+-4,5-bis diphenylphosphinomethyl-2,2-dimethyl-1,3-dioxolane, 2s,3s-+-1,4-bis diphenylphosphino-2,3-o-isopropylidene-2,3-butanediol, 4s,5s-+-bis diphenylphosphinomethyl-2,2-dimethyl-1,3-dioxolane, 4s,5s-4,5-bis diphenylphosphinomethyl-2,2-dimethyl-1,3-dioxolane, +-1,4-bis diphenylphosphino-1,4-dideoxy-2,3-o-isopropylidene-d-threitol, 2s,3s-+-2,3-o-isopropylidene-2,3-dihydroxy-1,4-bis diphenylphosphino butane
• PubChem CID: 3084647
• IUPAC Name: [(4S,5S)-5-(diphenylphosphanylmethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane
• SMILES: CC1(OC(C(O1)CP(C2=CC=CC=C2)C3=CC=CC=C3)CP(C4=CC=CC=C4)C5=CC=CC=C5)C

• Melting Point: 88°C to 90°C
• Quantity: 0.25 g
• Beilstein: 1630280
• Sensitivity: Air sensitive
• Solubility Information: Sparingly soluble in water at 25°C 2.1E-5g/L.
• Optical Rotation: +12.5° (c=4.6 in Benzene)
• Formula Weight: 498.55
• Percent Purity: 98%
• Chemical Name or Material: (+)-DIOP

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	253-307-9
TSCA	No
Recommended Storage	Keep cold

SDS