DKK3 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 4E6H6, Proteintech

Catalog No.	Quantity
50-173-7164	150 μL

Catalog No. 50-173-7164 Supplier Proteintech Group Inc Supplier No. 667581IG150UL

Description

Mouse Monoclonal Antibody

DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.

Specifications

• Antigen: DKK3
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 4E6H6
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: DKK3
• Gene Accession No.: Q9QUN9, Q9UBP4
• Gene Alias: Dickkopf 3, Dickkopf related protein 3, Dkk 3, DKK3, hDkk 3, REIC, RIG
• Gene Symbols: DKK3
• Host Species: Mouse
• Immunogen: DKK3 Fusion Protein Ag23615
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 171548, 27122, 50781, 664653
• Target Species: Human, Mouse, Pig, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b