DLL3 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS7860R

Catalog No. 50-198-8076

Description

Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.

Specifications

• Antigen: DLL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Dll3
• Gene Alias: delta like canonical Notch ligand 3; Delta3; delta-like 3; delta-like 3 (Drosophila); Delta-like protein 3; DLL3; Drosophila Delta homolog 3; M-Delta-3; pu; pudgy; SCDO1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10683
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q9NYJ7
• Gene Symbols: Dll3
• Immunogen: KLH conjugated synthetic peptide derived from human DLL3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG