Invitrogen™ DLL3 Recombinant Rabbit Monoclonal Antibody (11H27L9)

Catalog No.	Quantity
70-307-5	100 μg

Catalog No. 70-307-5 Supplier Invitrogen™ Supplier No. 703075

Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Mouse, Rat, Bovine.

Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.

Specifications

• Antigen: DLL3
• Applications: Western Blot
• Classification: Recombinant Monoclonal
• Clone: 11H27L9
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene: Dll3
• Gene Accession No.: Q9NYJ7
• Gene Alias: delta like canonical Notch ligand 3; Delta3; delta-like 3; delta-like 3 (Drosophila); delta-like protein 3; Dll3; Drosophila Delta homolog 3; M-Delta-3; pu; pudgy; SCDO1
• Gene Symbols: Dll3
• Host Species: Rabbit
• Immunogen: Protein corresponding to human DLL3 [aa514-aa618].
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10683
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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