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Invitrogen™ DLL3 Recombinant Rabbit Monoclonal Antibody (7H24L4)

Catalog No. 703623
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Catalog No. Quantity
70-362-3 100 μg
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Catalog No. 70-362-3 Supplier Invitrogen™ Supplier No. 703623
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Cat, Pig, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DLL3
Applications Immunocytochemistry
Classification Recombinant Monoclonal
Clone 7H24L4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Dll3
Gene Accession No. Q9NYJ7
Gene Alias delta like canonical Notch ligand 3; Delta3; delta-like 3; delta-like 3 (Drosophila); delta-like protein 3; Dll3; Drosophila Delta homolog 3; M-Delta-3; pu; pudgy; SCDO1
Gene Symbols Dll3
Host Species Rabbit
Immunogen Protein corresponding to human DLL3 [aa514-aa618].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10683
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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