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DMAP1 Polyclonal Antibody, Bethyl Laboratories

Goat Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A300217AT

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Catalog No. 50-155-7129


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others.DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localizedon chromosome 1p34.
Specifications

Specifications

DMAP1
Polyclonal
TBS with 0.1% BSA and 0.09% sodium azide
Q9NPF5
DMAP1
Between 50 and 100
20 μL
Primary
Human
Antibody
IgG
Western Blot
Unconjugated
DMAP1
RP5-891H21.2, DKFZp686L09142, DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, MEAF2, SWC4
Goat
Antigen affinity chromatography
RUO
55929
4° C
Liquid
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