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Invitrogen™ DMGDH Polyclonal Antibody
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Catalog No. PA550021
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PA550021 100 μL
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Catalog No. PA550021 Supplier Invitrogen™ Supplier No. PA550021
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Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total DMGDH protein.

This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DMGDH
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DMGDH
Gene Accession No. Q9UI17
Gene Alias 1200014D15Rik; AI787269; dimethylglycine dehydrogenase; dimethylglycine dehydrogenase precursor; dimethylglycine dehydrogenase, mitochondrial; Dmgdh; DMGDHD; EC 1.5.99.2; M2GD; ME2GLYDH
Gene Symbols DMGDH
Host Species Rabbit
Immunogen Synthesized peptide derived from C-terminal of human DMGDH.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29958
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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