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Invitrogen™ DNA Adenine Methylase Monoclonal Antibody (RB1)
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Catalog No. 01674049 Shop All Thermo Scientific Products
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01-674-049 100 μg
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Catalog No. 01-674-049 Supplier Invitrogen™ Supplier No. MA112717
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Description

Mouse Monoclonal Antibody

DNA Adenine Methylase Monoclonal Antibody for Western Blot

DNA adenine methylase (DAM) is an enzyme that methylates adenine residues in the 4-base pair DNA sequence, GATC. This methylation reaction has been shown to be crucial in a variety of cellular processes in bacteria. These include (i) the control of initiation of DNA replication (GATC occurs 11 times in the highly conserved bacterial origin of replication sequence); (ii) methyldirected mismatch repair; (iii) control of transposition of certain transposable DNA elements; and (iv) control of gene expression. With regard to gene expression, the recent report by Heithoff et al. (Science; 284:967-970; 1999) showed that the deletion of the DAM gene rendered Salmonella typhimurium totally avirulent.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNA Adenine Methylase
Applications Western Blot
Classification Monoclonal
Clone RB1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene Alias DAM; DAM methylase
Host Species Mouse
Immunogen Recombinant DNA Adenine Methylase protein.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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