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DNAJB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7088309 Shop All Proteintech Group Inc Products
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50-172-6643 150 μL
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Catalog No. 50-172-6643 Supplier Proteintech Group Inc Supplier No. 108381AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody detects both isoforms of DNAJB2 with MW between 32-40 kDa.

The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus. Two isoforms are produced due to alternative splicing.

Specifications

Antigen DNAJB2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DNAJB2
Gene Accession No. P25686, Q9QYI5
Gene Alias DnaJ protein homolog 1, DNAJB2, Heat shock 40 kDa protein 3, Heat shock protein J1, HSJ 1, HSJ1, HSPF3
Gene Symbols DNAJB2
Host Species Rabbit
Immunogen DNAJB2 Fusion Protein Ag1271
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3300, 56812, 689593
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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