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Invitrogen™ DNAJC13 Recombinant Rabbit Monoclonal Antibody (11H13L5)

Catalog No. 702773
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70-277-3 100 μg
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Catalog No. 70-277-3 Supplier Invitrogen™ Supplier No. 702773
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Cat, Goat, Sheep Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNAJC13
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 11H13L5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2-7.4
Gene DNAJC13
Gene Accession No. O75165
Gene Alias D030002L11Rik; DnaJ (Hsp40) homolog, subfamily C, member 13; DnaJ domain-containing protein RME-8; DnaJ heat shock protein family (Hsp40) member C13; dnaJ homolog subfamily C member 13; DNAJC13; Gm1124; j-domain containing protein, required for endocytosis; KIAA0678; mKIAA0678; PARK21; receptor mediated endocytosis RME-8; required for receptor-mediated endocytosis 8; Rme8; RME-8
Gene Symbols DNAJC13
Host Species Rabbit
Immunogen Protein corresponding to human DNAJC13 (aa1301-aa1354) GST Fusion.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23317, 235567
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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