Invitrogen™ DNase II Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519900

Catalog No. PIPA519900

Description

In Western blot applications, this antibody detects a band at ~40kDa, which represents the pro-enzyme of DNase II. A suggested positive control is human spleen tissue lysate. PA5-19900 can be used with blocking peptide PEP-0026.

DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Specifications

• Antigen: DNase II
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNASE2
• Gene Alias: acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; DNASE2; Dnase2a; DNL; Dnl2; lysosomal DNase II; R31240_2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1777
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O00115
• Gene Symbols: DNASE2
• Immunogen: A peptide near the carboxy terminus of human DNase II. The immunogen is located within the last 50 amino acids of DNase II.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG