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Invitrogen™ DNase II Polyclonal Antibody
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Catalog No. PIPA519900
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100 μg
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Catalog No. Quantity
PIPA519900 100 μg
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Catalog No. PIPA519900 Supplier Invitrogen™ Supplier No. PA519900
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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~40kDa, which represents the pro-enzyme of DNase II. A suggested positive control is human spleen tissue lysate. PA5-19900 can be used with blocking peptide PEP-0026.

DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNase II
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene DNASE2
Gene Accession No. O00115
Gene Alias acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; deoxyribonuclease II, lysosomal; deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; DNASE2; Dnase2a; DNL; Dnl2; lysosomal DNase II; R31240_2
Gene Symbols DNASE2
Host Species Rabbit
Immunogen A peptide near the carboxy terminus of human DNase II. The immunogen is located within the last 50 amino acids of DNase II.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1777
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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