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Invitrogen™ DNM1L Polyclonal Antibody
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Catalog No. PIPA595825
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100 μL
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PIPA595825 100 μL
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Catalog No. PIPA595825 Supplier Invitrogen™ Supplier No. PA595825
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Description

Rabbit Polyclonal Antibody

Positive Samples: MCF-7, NIH/3T3, Mouse brain, Mouse heart, Rat brain; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane Immunogen sequence: EEMQRIIQHC SNYSTQELLR FPKLHDAIVE VVTCLLRKRL PVTNEMVHNL VAIELAYINT KHPDFADACG LMNNNIEEQR RNRLARELPS AVSRDKSSKV PSALAPASQE PSPAASAEAD GKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW.

A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNM1L
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.59 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene DNM1L
Gene Accession No. O00429, O35303, Q8K1M6
Gene Alias 6330417M19Rik; AI450666; C-terminal region; Dlp1; dnm1l; Dnm1p/Vps1p-like protein; Dnml1; Dnmlp1; Drp1; DVLP; DYMPLE; dynamin 1 like; dynamin 1-like; dynamin family member proline-rich carboxyl-terminal domain less; Dynamin-1-like protein; Dynamin-1-like protein-like protein; Dynamin-like protein; dynamin-like protein 1; dynamin-like protein 4; Dynamin-like protein IV; dynamin-related protein 1; DYNIV 11; DYNIV-11; EC 3.6.5.5; EGK_03514; EMPF; FLJ41912; HDYNIV; N-terminal region; python; similar to dynamin 1-like; VPS1; zgc:66163
Gene Symbols DNM1L
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 437-736 of human DNM1L (NP_0361922).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10059, 114114, 74006
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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