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Invitrogen™ DNMT2 Polyclonal Antibody
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Catalog No. PIPA587964
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100 μL
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PIPA587964 100 μL
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Catalog No. PIPA587964 Supplier Invitrogen™ Supplier No. PA587964
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VHPQKYAMDV ENKIQEKNVE PNISFDGSIQ CSGKDAILFK LETAEEIHRK NQQDSDLSVK MLKDFLEDDT DVNQYLLPPK SLLRYALLLD IVQPTCRRSV CFTKGYGSYI EGTGSVLQTA EDVQVENIYK SLTNLSQEEQ ITKLLILKLR YFTPKEIANL LGFPPEFGFP EKITVKQRYR LLGNSLNVHV VAKLIKILYE; Positive Samples: SKOV3, 293T, DU145, HeLa, H460; Cellular Location: Nucleus.

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DNMT2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.64 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene TRDMT1
Gene Accession No. O14717
Gene Alias DMNT2; DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met2; met-2; MHSAIIP; PUMET; RNMT1; Rnmt2; RP11-406H21.1; Trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase; tRNA aspartic acid methyltransferase 1
Gene Symbols TRDMT1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 192-391 of human TRDMT1 (NP_0044031).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1787
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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